Gabriel phthalimide synthesis
The Gabriel phthalimide synthesis is a method for the preparation of primary amines from alkyl halides. The reaction involves the formation of an N-alkyl phthalimide intermediate, followed by its hydrolysis under basic conditions to give the corresponding primary amine. The general reaction scheme is as follows: R-X + phthalimide → R-NH-phthalimide R-NH-phthalimide + base →…